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| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | ZEB1 rabbit polyclonal antibody |
Gene Name: | Zinc finger E-box-binding homeobox 1 |
Synonyms: | ZEB1, zinc finger E-box binding homeobox 1, AREB6, BZP, DELTAEF1, FECD6, NIL2A, PPCD3, TCF8, ZFHEP, ZFHX1A |
Immunogen: | Recombinant protein corresponding to Mouse ZEB1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | P37275,Q64318,Q62947 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 1500 | brain, fetal brain, heart, lung, placenta, uterus |
Background
Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3').
Images
 | Immunohistochemistry of paraffin embedded human uterus using ZEB1 (GB11513) at dilution of 1:800 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse brain using ZEB1 (GB11513) at dilution of 1:800 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse heart using ZEB1 (GB11513) at dilution of 1:800 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse lung using ZEB1 (GB11513) at dilution of 1:800 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using ZEB1 (GB11513) at dilution of 1:800 (400x lens) |
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Immunohistochemistry of paraffin embedded rat lung using ZEB1 (GB11513) at dilution of 1:800 (400x lens) |
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Immunohistochemistry of paraffin embedded rat placenta using ZEB1 (GB11513) at dilution of 1:800 (400x lens) |
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Immunofluorescence of paraffin embedded mouse brain using ZEB1 (GB11513) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded mouse fetal brain using ZEB1 (GB11513) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded rat brain using ZEB1 (GB11513) at dilution of 1:500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
