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Anti-alpha 1 Fetoprotein Mouse mAb (100 μl)
| Reactivity: | H,R & H |
| Applications: | WB & IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Alpha-fetoprotein |
Synonyms: | AFP, Alpha 1 fetoprotein, Alpha fetoglobulin, alpha fetoprotein, FETA, HPAFP |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human AFP |
Uniprot ID: | P02771 |
Isotype: | IgG2b,κ |
Purity: | Affinity purification |
Subcellular location: | Secreted, Cytoplasm |
Predicted MW. / Observed MW. | 68 kDa / 68-72 kDa |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Rat | 1: 500-1: 1000 | liver, placenta |
IHC/IF | Human | 1: 500-1: 1000 | liver cancer |
Background
AFP, also known as Alpha-fetoprotein, is a major plasma protein in the fetus and its concentration is very low in the adult. So AFP is usually considered a marker of hepatocyte precursors. AFP can be detected at abnormally high concentrations in hepatocellular carcinomas as well as in the plasma and ascitic fluid of adults with hepatoma. High AFP concentrations have been correlated with tumor cell growth, indicating that AFP can serve as a tumor marker.
Images
 | Western blot analysis of AFP (GB12287) at dilution of 1: 1000 |
 | Immunohistochemistry analysis of paraffin embedded human liver cancer using AFP (GB12287) at dilution of 1: 1000 |
 | Immunohistochemistry analysis of paraffin embedded human liver cancer using AFP (GB12287) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
