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Anti-alpha Sarcoglycan Rabbit pAb (100 μl)
| Reactivity: | H,M,R & M |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | alpha Sarcoglycan rabbit polyclonal |
Gene Name: | Alpha-sarcoglycan |
Synonyms: | 50-DAG, 50DAG, A2, adhalin, ADL, Alpha SG, DAG2, DMDA2, Dystroglycan 2, LGMD2D, SCARMD1, SGCA |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse alpha Sarcoglycan |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm, Cytoskeleton |
Predicted MW. | 43 kDa |
Observed MW. | 55 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 300-1: 600 | heart, skeletal muscle |
IHC | Mouse | 1: 300-1: 600 | skeletal muscle |
Background
Alpha-sarcoglycan is a member of the sarcoglycan-sarcospan complex (SG-SSPN), which is constituted by α/ɛ-, β-, γ-, and δ-SGs as well as SSPN. Alpha-sarcoglycan gene expression is exclusive of striated muscle and is finely regulated during myogenic differentiation, where the amount of alpha-sarcoglycan transcript is selectively increased after differentiation to myotubes (MTs). Alpha sarcoglycan's disruption causes limb-girdle muscular dystrophy.
Images
| Western blot analysis of SGCA (GB113664) at dilution of 1: 600 |
| Immunohistochemistry analysis of paraffin-embedded mouse skeletal muscle using SGCA (GB113664) at dilution of 1: 600 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
