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Anti-eIF2B3 Rabbit pAb (100 μl)
| Reactivity: | H & H |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | eIF2B3 rabbit polyclonal antibody |
Gene Name: | Eukaryotic translation initiation factor 2B, subunit 3 |
Synonyms: | EIF-2B, EIF2Bgamma, EIF2B3 |
Immunogen: | Recombinant protein corresponding to Mouse eIF2B3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Predicted MW. | 50 kDa |
Observed MW. | 50 kDa |
Uniprot ID: | B1AUN2 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | MCF7 |
IHC/IF | Human | 1: 1000-1: 2000 | renal cancer, ovarian cancer, liver, liver cancer |
Background
The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Images
 | Western blot analysis of EIF2B3 (GB114048) at dilution of 1: 1000 |
 | Immunohistochemistry of paraffin embedded human hepatobiliary cancer using EIF2B3 (GB114048) at dilution of 1: 1000 |
 | Immunohistochemistry of paraffin embedded human renal cancer using EIF2B3 (GB114048) at dilution of 1: 1500 |
 | Immunohistochemistry of paraffin embedded human renal cancer using EIF2B3 (GB114048) at dilution of 1: 1500 |
 | Immunohistochemistry of paraffin embedded human liver cancer using EIF2B3 (GB114048) at dilution of 1: 1500 |
 | Immunofluorescence of paraffin embedded human hepatobiliary cancer using EIF2B3 (GB114048) at dilution of 1: 1000 |
 | Immunofluorescence of paraffin embedded human liver cancer using EIF2B3 (GB114048) at dilution of 1: 1000 |
 | Immunofluorescence of paraffin embedded human ovarian cancer using EIF2B3 (GB114048) at dilution of 1: 2000 |
 | Immunofluorescence of paraffin embedded human liver using EIF2B3 (GB114048) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |