Your shopping cart is empty!
Anti-mH2A2 Rabbit pAb (100 μl)
| Reactivity: | H & R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | mH2A2 rabbit polyclonal antibody |
Gene Name: | Core histone macro-H2A.2 |
Synonyms: | Core histone macro H2A.2, H2A histone family, member Y2, H2AFY2, histone, Histone macroH2A2, macroH2A2, mH2A2 |
Immunogen: | Recombinant protein corresponding to Mouse mH2A2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Chromosome |
Predicted MW. | 40 kDa |
Observed MW. | 40 kDa |
Uniprot ID: | Q8CCK0 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | HepG2, MCF7 |
IHC/IF | Rat | 1: 1000-1: 2000 | testis, brain |
Background
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
Images
 | Western blot analysis of Macroh2a2 (GB114033) at dilution of 1: 1000 |
 | Immunohistochemistry of paraffin embedded rat brain using Macroh2a2 (GB114033) at dilution of 1: 1500 |
 | Immunohistochemistry of paraffin embedded rat testis using Macroh2a2 (GB114033) at dilution of 1: 1500 |
 | Immunofluorescence of paraffin embedded rat brain using Macroh2a2 (GB114033) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
