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| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | SEC14 domain and spectrin repeat-containing protein 1 |
Synonyms: | Protein Solo, SEC14 and spectrin domains 1, SESTD1, SOLO |
Immunogen: | Recombinant protein corresponding to Mouse SESTD1 |
Uniprot ID: | Q80UK0 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoskeleton |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 800-1: 1600 | esophageal carcinoma, renal carcinoma, brain |
Background
May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1 (By similarity).
Images
| Immunohistochemistry analysis of paraffin embedded human esophageal carcinoma using SESTD1 (GB114463) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded human renal carcinoma using SESTD1 (GB114463) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded rat Brain using SESTD1 (GB114463) at dilution of 1: 1600 |
| Immunofluorescence analysis of paraffin embedded human ovarian cancer using SESTD1 (GB114463) at dilution of 1: 800 |
| Immunofluorescence analysis of paraffin embedded mouse Brain using SESTD1 (GB114463) at dilution of 1: 800 |
| Immunofluorescence analysis of paraffin embedded rat Brain using SESTD1 (GB114463) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
