Reactivity: | H & H |
Applications: | IHC & IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Spinophilin/Neurabin 2 rabbit polyclonal |
Gene Name: | Neurabin-2 |
Synonyms: | PPP1R9B, PPP1R6, PPP1R9, SPINO, Spn, protein phosphatase 1 regulatory subunit 9B, p130, Spinophilin, PP1bp134, Neurabin II, Neural tissue specific F actin binding protein II |
Immunogen: | Recombinant protein corresponding to Human Neurabin 2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Nucleus, Cytoskeleton |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human | 1: 1000-1: 2000 | stomach |
IF | Human | 1: 500-1: 1000 | stomach |
Background
Neurabin-2 is a protein that in humans is encoded by the PPP1R9B gene. PPP1R9B has been shown to interact with PPP1CB, PPP1CA, Dopamine receptor D2, P16, PPP1CC, T-cell lymphoma invasion and metastasis-inducing protein 1 and PPP1R2. Neurabin-2, also known as Spinophilin, is a regulatory subunit of protein phosphatase-1 catalytic subunit and is highly enriched in dendritic spines, specialized protrusions from dendritic shafts that receive most of the excitatory input in the central nervous system.
Images
Immunohistochemistry analysis of paraffin-embedded human stomach using Neurabin 2 (GB11653) at dilution of 1:1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |