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Anti-Survivin Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Survivin rabbit polyclonal antibody |
Gene Name: | Baculoviral IAP repeat-containing protein 5 |
Synonyms: | API4, Apoptosis inhibitor 4, Apoptosis inhibitor |
Immunogen: | Recombinant protein corresponding to Mouse Survivin |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Spindle, Nucleus, Cytoplasm, |
Predicted MW. | 16 kDa |
Observed MW. | 16 KDa |
Uniprot ID: | O70201, O15392, Q9JHY7 |
Applications
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 600-1: 800 | colon, testis, skin |
IHC/IF | Mouse, Rat | 1: 400-1: 800 | lung, lung+LPS, spleen |
Background
Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules.
Images
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Western blot analysis of Survivin (GB11177) at dilution of 1: 600 |
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Immunohistochemistry of paraffin embedded mouse spleen using survivin (GB11177) at dilution of 1: 400 (400x lens) |
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Immunohistochemistry of paraffin embedded rat spleen using survivin (GB11177) at dilution of 1: 800 (400x lens) |
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Immunofluorescence of paraffin embedded mouse lung using survivin (GB11177) at dilution of 1: 600 (300x lens) |
| Immunofluorescence of paraffin embedded mouse lung+LPS using survivin (GB11177) at dilution of 1: 800 (200x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
