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| Reactivity: | H,M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Mitogen-activated protein kinase kinase kinase 7 |
Synonyms: | MAP3K7, MEKK7, TAK1, TGF1a, Mitogen-activated protein kinase kinase kinase 7, FMD2, CSCF, MAPKKK7, M3K7 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse TAK1 |
Uniprot ID: | Q62073 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm |
Predicted MW. / Observed MW. | 64 kDa / 75 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 500-1: 1000 | spleen, lung, uterine |
IHC/IF | Mouse, Rat | 1: 500-1: 2000 | brain, spleen |
Background
Mitogen-activated protein kinase kinase kinase 7 (MAP3K7), also known as TAK1, is an enzyme which belongs to a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. TAK1 is a central regulator of cell death and is activated through a diverse set of intra- and extracellular stimuli.
Images
|
Western blot analysis of TAK1 (GB11700) at dilution of 1: 500 |
| Immunohistochemistry analysis of paraffin embedded rat cerebral infarction using TAK1 (GB11700) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat brain using TAK1 (GB11700) at dilution of 1: 500 |
| Immunohistochemistry analysis of paraffin embedded mouse brain using TAK1 (GB11700) at dilution of 1: 1000 |
| Immunofluorescent analysis of paraffin embedded rat spleen using TAK1 (GB11700) at dilution of 1: 1000 |
| Immunofluorescent analysis of paraffin embedded mouse lymph using TAK1 (GB11700) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
