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Anti-TCPTP Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TCPTP rabbit polyclonal antibody |
Gene Name: | Tyrosine-protein phosphatase non-receptor type 2 |
Synonyms: | Protein-tyrosine phosphatase PTP-S, Ptpn2, TCPTP, PTP2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse TCPTP |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm, Nucleus |
Uniprot ID: | P35233 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 500-1: 1800 | fallopian tubes, kidney, liver, lung, ovary, testis, thymus |
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling.
Images
 | Immunohistochemistry of paraffin embedded rat fallopian tubes using PTPN2 (GB111074) at dilution of 1:900 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat kidney using PTPN2 (GB111074) at dilution of 1:900 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat liver using PTPN2 (GB111074) at dilution of 1:900 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat ovary using PTPN2 (GB111074) at dilution of 1:900 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat thymus using PTPN2 (GB111074) at dilution of 1:900 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse testis using PTPN2 (GB111074) at dilution of 1:500 (400x lens) |
 | Immunofluorescence of paraffin embedded rat liver using PTPN2 (GB111074) at dilution of 1:500 (400x lens) |
 | Immunofluorescence of paraffin embedded rat lung using PTPN2 (GB111074) at dilution of 1:500 (400x lens) |
 | Immunofluorescence of paraffin embedded rat ovary using PTPN2 (GB111074) at dilution of 1:500 (400x lens) |
 | Immunofluorescence of paraffin embedded rat thymus using PTPN2 (GB111074) at dilution of 1:500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
