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Anti-TDP43 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TDP43 rabbit polyclonal antibody |
Gene Name: | TAR DNA-binding protein 43 |
Synonyms: | TDP-43, Tardbp, ALS10, Tdp43, TAR DNA binding protein |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse TDP43 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Uniprot ID: | Q921F2 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1:200-1:400 | brain, heart, testis |
Background
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene.
Images
| Immunohistochemistry of paraffin embedded mouse testis using TARDBP (GB112160) at dilution of 1:200 (360x lens) |
| Immunohistochemistry of paraffin embedded mouse brain using TARDBP (GB112160) at dilution of 1:200 (400x lens) |
| Immunohistochemistry of paraffin embedded rat testis using TARDBP (GB112160) at dilution of 1:200 (250x lens) |
| Immunohistochemistry of paraffin embedded rat brain using TARDBP (GB112160) at dilution of 1:200 (400x lens) |
| Immunohistochemistry of paraffin embedded rat heart using TARDBP (GB112160) at dilution of 1:200 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse testis using TARDBP (GB112160) at dilution of 1:200 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
