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| Reactivity: | M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TFF2 rabbit polyclonal antibody |
Gene Name: | Trefoil factor 2 |
Synonyms: | Spasmolytic polypeptide, SP, Sml1, spasmolytic protein 1, Spasmolysin, Trefoil factor 2 precursor |
Immunogen: | Recombinant protein corresponding to Mouse TFF2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 14 kDa |
Observed MW. | 14 kDa |
Uniprot ID: | Q03404 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse | 1: 500-1: 1000 | stomach, pancreas |
Background
The trefoil factor family (TFF), comprises of three polypeptides, TFF1, TFF2 and TFF3 (7-12 kDa), secreted to mucosal surfaces by mucus producing cells, prominently in the gastrointestinal tract. TFF2, also known as spasmolytic polypeptide, is a low-molecular weight protein, expressed in mucous neck cells of the fundus and glands at the base of the antrum in normal human stomach. TFF2 could Inhibit gastrointestinal motility and gastric acid secretion. However, recent studies suggest that TFF2 could also play an important role in the immune system.
Images
| Western blot analysis of TFF2 (GB111645) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
