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Anti-TGF beta 1 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TGF beta 1 rabbit polyclonal antibody |
Gene Name: | Transforming growth factor beta-1 proprotein |
Synonyms: | CED, DPD1, LAP, TGF beta 1, tgf beta1, TGFB, TGFB1, TGFbeta, tgfbeta1, tgf-beta1, TGFβ, TGFβ1, TGF-β1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse TGF beta 1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 44 kDa |
Observed MW. | 50 kDa |
Uniprot ID: | P01137 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | HeLa, A549, K562, HEK293 |
Background
TGFB, also named as LAP and TGFB1, is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for it. TGFB positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. It is highly expressed in bone.
Images
| Western blot analysis of TGFb1 (GB111876) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
