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Anti-TGF beta Receptor II Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | TGF-beta receptor type-2 |
Synonyms: | TGFR-2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II, TGF-beta receptor type II, TbetaR-II, Tgfbr2 |
Immunogen: | Recombinant protein corresponding to Mouse TGF beta Receptor II |
Uniprot ID: | Q62312 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 67 kDa / 67 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 500-1: 1000 | kidney, brain, heart |
Background
This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors.
Images
 | Western blot analysis of TGFbRII (GB112244) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
