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Anti-THEM2 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | THEM2 rabbit polyclonal antibody |
Gene Name: | Acyl-coenzyme A thioesterase 13 |
Synonyms: | Acyl-CoA thioesterase 13, Thioesterase superfamily member 2, Acot13, Them2, hypothalamus protein HT012, PNAS27, 15 Kd protein |
Immunogen: | Recombinantproteincorrespondingto Mouse THEM2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 15 kDa |
Observed MW. | 15 kDa |
Uniprot ID: | Q9CQR4 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | heart, liver, kidney, brain |
Background
THEM2, also known as ACOT13, belongs to the hotdog-fold superfamily and possesses thioesterase activity, with greater activity observed with longer chain acyl-CoAs such as myristoyl- and palmitoyl-CoA. THEM2 is highly expressed in several tissues such as heart, kidney, liver and brain and has been shown to be co-localized with beta-tubulin on microtubules. THEM2 interacts with StarD, a protein that plays a key role in fatty acid metabolism, and the addition of StarD to THEM2 increased its catalytic activity, suggesting that THEM2 plays a significant role in the metabolism of fatty acids.
Images
| Western blot analysis of THEM2 (GB111650) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
