Reactivity: | M |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | TMEM158 rabbit polyclonal antibody |
Gene Name: | Transmembrane protein 158 |
Synonyms: | 40 kDa BINP-binding protein, p40BBP, Ras-induced senescence protein 1, Tmem158, Mbbp, Ris1, BBP, HBBP |
Immunogen: | Recombinant protein corresponding to Mouse TMEM158 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 29 kDa |
Observed MW. | 35 kDa |
Uniprot ID: | Q6F5E0 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse | 1: 500-1:1000 | ovary, uterus |
Background
TMEM158 is a 286 amino acid protein encoded by a gene mapping to human chromosome 3. Chromosome 3 is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
Images
Western blot analysis of TMEM158 (GB112358) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |