Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | TMS1/ASC rabbit polyclonal antibody |
Gene Name: | Apoptosis-associated speck-like protein containing a CARD |
Synonyms: | ASC, CARD5, hASC, PYCARD, PYD and CARD domain containing, TMS, TMS-1, TMS1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human TMS1/ASC |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 22 kDa |
Observed MW. | 22-25 kDa |
Uniprot ID: | Q9ULZ3 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 300-1: 600 | HL-60, THP-1, MCF-7 |
Background
PYCARD , also known as ASC or TMS1, is a 195 amino acid protein containing an N-terminal Pyrin-like domain (PYD) and an 87 residue C-terminal Caspase-associated recruitment domain (CARD). It promotes caspase-mediated apoptosis which is mediated predominantly through the activation of caspase-9.
Images
Western blot analysis of ASC (GB114054) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |