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Anti-TNNC1 Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TNNC1 rabbit polyclonal antibody |
Gene Name: | Troponin C, slow skeletal and cardiac muscles |
Synonyms: | Tnnc1, TNNC1, CMD1Z, CMH13, TN-C, TNC, TNNC, Troponin C type 1, Troponin C1, Slow skeletal and cardiac type |
Immunogen: | Recombinant protein corresponding to Mouse TNNC1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Predicted MW. | 18 kDa |
Observed MW. | 18 kDa |
Uniprot ID: | P19123 |
Images
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | heart, lung, skeletal muscle, liver |
IHC/IF | Mouse, Rat | 1: 800-1: 3000 | heart, lung, myocardial infarction, Skeletal muscle |
Background
Troponin I (TnI), troponin T (TnT) , troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
Images
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Western blot analysis of Tncc (GB111243) at dilution of 1: 500 |
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Immunohistochemistry of paraffin embedded mouse myocardial infarction using TnCC (GB111243) at dilution of 1: 800 (400x lens) |
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Immunohistochemistry of paraffin embedded rat heart using TnCC (GB111243) at dilution of 1: 800 (400x lens) |
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Immunofluorescence of paraffin embedded mouse lung using TnCC (GB111243) at dilution of 1: 1600 (400x lens) |
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Immunofluorescence of paraffin embedded mouse skeletal muscle using TnCC (GB111243) at dilution of 1: 1600 (400x lens) |
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Immunofluorescence of paraffin embedded rat heart using TnCC (GB111243) at dilution of 1: 1600 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
