Your shopping cart is empty!
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Thyroid peroxidase (TPO) (EC 1.11.1.8) |
Gene ID: | 7173 |
Immunogen: | Synthesized peptide derived from human Thyroid Peroxidase (TPO) |
Uniprot ID: | P07202 |
Source: | Mouse/IgG2b, Kappa |
Concentration: | 1 mg/ml |
Purity: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Product Usage Information
IHC/IF | Human | 1: 200-1: 500 | follicular thyroid carcinoma |
Background
thyroid peroxidase(TPO) Homo sapiens This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined.
Images
| Immunohistochemistry analysis of paraffin embedded human follicular thyroid carcinoma using Thyroid Peroxidase/TPO (GB14160) at dilution of 1: 200 |
Storage
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
