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Anti-TRIB1 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Tribbles homolog 1 |
Synonyms: | C8FW, GIG2, TRB1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse TRIB1 |
Uniprot ID: | Q8K4K4 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 41 kDa / 41 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 800-1: 1600 | skeletal muscle |
Background
Adapter protein involved in protein degradation by interacting with COP1 ubiquitin ligase . Promotes CEBPA degradation and inhibits its function . Controls macrophage, eosinophil and neutrophil differentiation via the COP1-binding domain . Regulates myeloid cell differentiation by altering the expression of CEBPA in a COP1-dependent manner .Interacts with MAPK kinases and regulates activation of MAP kinases, but has no kinase activity (By similarity).
Images
| Western blot analysis of TRIB1 (GB114317) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
