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Anti-TROP2 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TROP2 rabbit polyclonal antibody |
Gene Name: | Tumor-associated calcium signal transducer 2 |
Synonyms: | Cell surface glycoprotein Trop-2, Tacstd2, Trop2, Epithelial glycoprotein 1, M1S1, GA7331, Membrane component chromosome 1 surface marker 1 |
Immunogen: | Recombinant protein corresponding to Mouse TROP2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Membrane |
Uniprot ID: | Q8BGV3 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 500-1: 1800 | bladder, kidney |
Background
TROP2 is a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member of a family including at least two type I membrane proteins. It transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of its gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.
Images
| Immunohistochemistry of paraffin embedded mouse kidney using TROP2 (GB111809) at dilution of 1:900 (400x lens) |
| Immunohistochemistry of paraffin embedded rat bladder using TROP2 (GB111809) at dilution of 1:1800 (400x lens) |
| Immunohistochemistry of paraffin embedded rat kidney using TROP2 (GB111809) at dilution of 1:900 (400x lens) |
| Immunofluorescence of paraffin embedded mouse bladder using TROP2 (GB111809) at dilution of 1:600 (300x lens) |
| Immunofluorescence of paraffin embedded mouse kidney using TROP2 (GB111809) at dilution of 1:600 (300x lens) |
| Immunofluorescence of paraffin embedded rat kidney using TROP2 (GB111809) at dilution of 1:600 (300x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
