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Anti-TRPV6 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Transient receptor potential cation channel subfamily V member 6 |
Synonyms: | ABP/ZF, Calcium transport protein 1, CaT L, CaT like, CAT1, CATL, ECAC2, Epithelial calcium channel 2, HSA277909, LP6728 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse TRPV6 |
Uniprot ID: | Q91WD2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 87 kDa / 70 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | colon, liver |
Background
Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine . Important for normal Ca(2+) ion homeostasis in the body, including bone and skin . The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification. Inactivation includes both a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism; the latter may be regulated by phosphorylation . In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner . Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating .
Images
| Western blot analysis of TRPV6 (GB114616) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
