Your shopping cart is empty!
Anti-pan alpha Tubulin Mouse mAb (50 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Tubulin alpha-1A chain |
Immunogen: |
Synthesized peptide derived from human α-tubulin |
Uniprot ID: |
Q71U36, P68363 |
Source: |
Mouse |
Concentration: |
1 mg/ml |
Purity: |
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Product Usage Information
IHC/IF |
Human |
1: 200-1: 500 |
colon cancer, renal carcinoma |
Background
Alpha Tubulin is a part of a heterodimer consisting of alpha and beta tubulin subunits. The alpha and beta tubulins, which are each about 55 kDa MW, are homologous but not identical. Alpha-beta tubulin heterodimer is the basic building block of microtubules, and this intracellular cylindrical filamentous structure is present in almost eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species.
Images
|
Immunohistochemistry analysis of paraffin embedded human colon cancer using P-α-tubulin (GB14162) at dilution of 1: 200 |
|
Immunohistochemistry analysis of paraffin embedded human renal carcinoma using P-α-tubulin (GB14162) at dilution of 1: 200 |
Storage
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
