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Anti-TULP3 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Tubby-related protein 3 |
Synonyms: | tubby like protein 3, Tubby related protein 3, TUBL3, TULP3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse TULP3 |
Uniprot ID: | O88413 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 51 kDa / 55 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | kidney |
Background
Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT-A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide (phosphoinositide) lipids. Both IFT-A- and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis. During adipogenesis, regulates ciliary trafficking of FFAR4 in preadipocytes.
Images
| Western blot analysis of TULP3 (GB114664) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
