Your shopping cart is empty!
Anti-Thorase Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Thorase rabbit polyclonal antibody |
Gene Name: | Outer mitochondrial transmembrane helix translocase |
Synonyms: | AAA+ ATPase Thorase, AFDC1, Atad1, Thorase, ATPase Thorase, ATPase family AAA domain-containing protein 1 |
Immunogen: | Recombinant protein corresponding to Human Thorase |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 41 kDa |
Observed MW. | 41 kDa |
Uniprot ID: | Q8NBU5 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 300-1: 800 | brain, testis |
Background
Outer mitochondrial translocase required to remove mislocalized tail-anchored transmembrane proteins on mitochondria 1. Specifically recognizes and binds tail-anchored transmembrane proteins: acts as a dislocase that mediates the ATP-dependent extraction of mistargeted tail-anchored transmembrane proteins from the mitochondrion outer membrane (By similarity). Also plays a critical role in regulating the surface expression of AMPA receptors (AMPAR), thereby regulating synaptic plasticity and learning and memory (By similarity). Required for NMDA-stimulated AMPAR internalization and inhibition of GRIA1 and GRIA2 recycling back to the plasma membrane; these activities are ATPase-dependent .
Images
 | Western blot analysis of ATAD1 (GB113891) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |