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Anti-Topoisomerase I Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Topoisomerase I rabbit polyclonal antibody |
Gene Name: | DNA topoisomerase 1 |
Synonyms: | Top1, Top-1, NUP98 fusion gene, Type I DNA topoisomerase, TopoisomeraseI |
Immunogen: | Recombinant protein corresponding to Mouse Topoisomerase I |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 91 kDa |
Observed MW. | 100 kDa |
Uniprot ID: | P11387 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | HeLa, MCF-7, SW480, K562 |
Background
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.
Images
| Western blot analysis of TOP1 (GB112458) at dilution of 1: 500 |
| Western blot analysis of TOP1 (GB112458) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
