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Anti-Topoisomerase II alpha Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Topoisomerase II alpha rabbit polyclonal antibody |
Gene Name: | DNA topoisomerase 2-alpha |
Synonyms: | DNA topoisomerase II, alpha isozyme, TOP2A, Top-2, Top2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse TOP2A |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Uniprot ID: | P11388, Q01320, P41516 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 1500-1: 3000 | brain, breast cancer, colon, placenta, testis, thymus |
Background
TOP2A, also named as TOP2, belongs to the type II topoisomerase family. Topoisomerase II makes double-strand breaks. TOP2 control the topological states of DNA by transient breakage and subsequent rejoining of DNA strands.
Images
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Immunohistochemistry of paraffin embedded human breast cancer using TOP2A (GB111293) at dilution of 1:1400 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse colon using TOP2A (GB111293) at dilution of 1:1400 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse placenta using TOP2A (GB111293) at dilution of 1:1400 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse testis using TOP2A (GB111293) at dilution of 1:1400 (400x lens) |
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Immunohistochemistry of paraffin embedded rat colon using TOP2A (GB111293) at dilution of 1:1400 (400x lens) |
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Immunohistochemistry of paraffin embedded rat placenta using TOP2A (GB111293) at dilution of 1:1400 (400x lens) |
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Immunofluorescence of paraffin embedded human colon using TOP2A (GB111293) at dilution of 1:1400 (400x lens) |
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Immunofluorescence of paraffin embedded mouse brain using TOP2A (GB111293) at dilution of 1:1400 (400x lens) |
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Immunofluorescence of paraffin embedded mouse testis using TOP2A (GB111293) at dilution of 1:1400 (400x lens) |
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Immunofluorescence of paraffin embedded rat thymus using TOP2A (GB111293) at dilution of 1:1400 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
