Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Trefoil Factor 3 rabbit polyclonal antibody |
Gene Name: | Trefoil factor 3 |
Synonyms: | Intestinal trefoil factor, mITF, Tff3, Itf, hITF, ITF, P1B, Polypeptide P1.B, TFI |
Immunogen: | Recombinant protein corresponding to Mouse Tff3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Uniprot ID: | Q62395, Q03191 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 500-1: 2000 | colon, small intestine, uterus |
Background
Trefoil factor 3 (TFF3) belongs to the TFF-domain peptide family which consists of three small secreted proteins (TFF1, TFF2, TFF3) that are expressed by mucous-secreting epithelia. TFF3 is a major constituent in the goblet cells in small and large intestines, especially a typical secretary peptide of the normal human antral and pyloric gastric mucosa. TFF3 is essential in regulating cell migration and maintaining normal GI mucosal integrity. TFF3 is involved in tumor cell scattering, angiogenesis, and invasion.
Images
Immunohistochemistry of paraffin embedded mouse small intestine using TFF3 (GB111419) at dilution of 1:2000 (300x lens) |
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Immunohistochemistry of paraffin embedded rat small intestine using TFF3 (GB111419) at dilution of 1:2000 (300x lens) | |
Immunohistochemistry of paraffin embedded rat uterus using TFF3 (GB111419) at dilution of 1:2000 (300x lens) |
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Immunofluorescence of paraffin embedded mouse colon using TFF3 (GB111419) at dilution of 1:1000 (300x lens) | |
Immunofluorescence of paraffin embedded mouse small intestine using TFF3 (GB111419) at dilution of 1:1000 (300x lens) | |
Immunofluorescence of paraffin embedded rat colon using TFF3 (GB111419) at dilution of 1:500 (300x lens) | |
Immunofluorescence of paraffin embedded rat small intestine using TFF3 (GB111419) at dilution of 1:1000 (300x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |