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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | UBR7 rabbit polyclonal |
Gene Name: | Putative E3 ubiquitin-protein ligase UBR7 |
Synonyms: | N-recognin-7, RING-type E3 ubiquitin transferase UBR7, Ubr7, C14orf130 |
Immunogen: | Recombinant protein corresponding to Mouse UBR7 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 48 kDa |
Observed MW. | 55 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | testis |
Background
UBR7 (C14orf130), is a 425-amino-acid putative E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. The N-end rule pathway is a ubiquitin-dependent system where E3 ligases called N-recognins, including UBR1, UBR2 and UBR7 (N-recognin-7), leading to target protein ubiquitination and subsequent degradation . UBR7 contains a PHD-type zinc finger and a UBR-type zinc finger domain , and probably undergoes acetylation . Till date its precise function is not well known.
Images
 | Western blot analysis of UBR7 (GB113023) at dilution of 1: 2000 Lane 1: HeLa cell lysate Lane 2: Jurkat cell lysate Lane 3: Mouse testis tissue lysate Lane 4: Rat testis tissue lysate |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
