Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | UDP-glucuronosyltransferase 1-6 |
Synonyms: | GNT1, HLUGP, HLUGP1, MGC29860, UDPGT, UGT1, UGT1A6S, UGT1F |
Immunogen: | Recombinant protein corresponding to Mouse UGT1A6 |
Uniprot ID: | Q64435 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 60 kDa / 61 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | MCF7, kidney, liver |
Background
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Conjugates small planar phenolic molecules such as 4-nitrophenol, 1-naphthol, and 4-methylumbelliferone. The bulky phenol 4-hydroxybiphenyl, androgens and estrogens are not substrates. 2-hydroxybiphenyl is an excellent substrate.
Images
WB analysis of UGT1A6(GB115677). Sample: Protein treated by RIPA Lysis Buffer (G2002). |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |