Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Cytochrome b-c1 complex subunit 2, mitochondrial |
Synonyms: | Complex III subunit 2, Core protein II, QCR2, UQCR2, UQCRC2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse UQCRC2 |
Uniprot ID: | Q9DB77 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 48 kDa / 48 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 800-1: 1500 | liver, heart |
Background
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c,with protons being carried across the membrane as hydrogens on the quinol.
Images
Western blot analysis of UQCRC2 (GB114796) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |