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Anti-USP27X Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | USP27X rabbit polyclonal antibody |
Gene Name: | Ubiquitin carboxyl-terminal hydrolase 27 |
Synonyms: | Deubiquitinating enzyme 27, Usp27, Usp27x, Ubiquitin thioesterase 27, X-linked ubiquitin carboxyl-terminal hydrolase 27, Ubiquitin-specific-processing protease 27 |
Immunogen: | Recombinant protein corresponding to Mouse USP27X |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Uniprot ID: | Q8CEG8 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 300-1: 1500 | cerebellum, spinal cord, testis |
Background
The USP27X is a deubiquitinase that can reduce the levels of BCL2L11/BIM ubiquitination and stabilize BCL2L11 in response to the RAF-MAPK-degradation signal. By acting on BCL2L11 levels, may counteract the anti-apoptotic effects of MAPK activity.
Images
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Immunohistochemistry of paraffin embedded mouse cerebellum using USP27 (GB111100) at dilution of 1:700 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse spinal cord using USP27 (GB111100) at dilution of 1:700 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat cerebellum using USP27 (GB111100) at dilution of 1:700 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat spinal cord using USP27 (GB111100) at dilution of 1:700 (400x lens) |
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Immunofluorescence of paraffin embedded mouse cerebellum using USP27 (GB111100) at dilution of 1:1500 (400x lens) |
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Immunofluorescence of paraffin embedded rat spinal cord using USP27 (GB111100) at dilution of 1:1500 (400x lens) |
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Immunofluorescence of paraffin embedded rat testis using USP27 (GB111100) at dilution of 1:1500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
