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Anti-VE Cadherin Mouse mAb (100 μl)
| Reactivity: | M |
| Applications: | WB |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Cadherin-5 |
Synonyms: | 7B4, 7B4 antigen, Cadherin 5, CD144, CDH5, FLJ17376, Vascular endothelial cadherin, VE cadherin, VE-cadherin |
Immunogen: | Mouse recombinant VE-cadherin protein expressed in HEK293 cells |
Uniprot ID: | P55284 |
Isotype: | IgG2a,κ |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 87 kDa / 90-130 kDa |
Product Usage Information
WB | Mouse | 1: 500-1: 1000 | lung, placenta |
Background
This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance.
Images
| Western blot analysis of VE-cadherin (GB12013) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
