Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Vascular endothelial growth factor receptor 1 |
Synonyms: | FLT, FLT 1, FLT1, FLT-1, Fms like tyrosine kinase 1, FRT, sflt1, Tyrosine protein kinase FRT, VEGF receptor 1, VEGFR 1, VEGFR1, VEGFR-1 |
Immunogen: | Recombinant protein corresponding to Human VEGF Receptor 1 |
Uniprot ID: | P17948 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 151 kDa / 180 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 400-1: 800 |
Background
Vascular endothelial growth factor receptor-1 (VEGFR-1, FLT-1) is a receptor tyrosine kinase belonging to the VEGFR family. VEGF is a key regulator of physiological angiogenesis and has also been implicated in pathological angiogenesis associated with tumors, intraocular neovascular disorders and other conditions. The biological effects of VEGF are mediated by VEGFR-1 and VEGFR-2. Both the two receptors have seven immunoglobulin-like repeats in the extracellular domain, a single transmembrane region and a tyrosine kinase domain.
Images
Western blot analysis of VEGFR1 (GB114200) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |