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Anti-VEGF Receptor 3 Rabbit pAb (100 μl)
| Reactivity: | H & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Vascular endothelial growth factor receptor 3 |
Synonyms: | VEGFR-3, Fms-like tyrosine kinase 4, FLT-4, Tyrosine-protein kinase receptor FLT4, Flt4, Vegfr3, Soluble VEGFR3 variant 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse VEGF Receptor 3 |
Uniprot ID: | P35917 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm, Nucleus, Secreted |
Predicted MW. / Observed MW. | 153 kDa / 130 kDa |
Product Usage Information
WB | Human | 1: 500-1: 1000 | HeLa, A431, HepG2, Raji, PC-3 |
IHC/IF | Mouse, Rat | 1: 400-1: 1200 | corpus striatum, lung |
Background
Vascular endothelial growth factors (VEGFs) are a family of closely related growth factors having a conserved pattern of eight cysteine esidues and sharing common VEGF receptors. VEGFs stimulate the proliferation of endothelial cells, induce angiogenesis, and increase vascular permeability in both large and small vessels. The mitogenic activity of VEGFs appears to be mediated by specific VEGF receptors. VEGF Receptor 3 is one of the five receptor tyrosine kinases (RTKs) (VEGF Receptor 1/Flt1, VEGF Receptor 2/KDR/Flk1, VEGF Receptor 3/Flt4, tie1 and tek/tie2) whose expression is almost exclusively restricted to endothelial cells.
Images
| Western blot analysis of VEGF Receptor 3 (GB112339) at dilution of 1: 1000 |
| Immunofluorescence analysis of paraffin embedded mouse corpus striatum using Flt4 (GB112339) at dilution of 1: 1200 |
| Immunofluorescence analysis of paraffin embedded mouse lung using Flt4 (GB112339) at dilution of 1: 400 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
