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Anti-Vimentin Mouse mAb (100 μl)
| Reactivity: | H & H,R |
| Applications: | WB & IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Vimentin |
Synonyms: | VIM, CTRCT30, HEL113 |
Immunogen: | Recombinant protein corresponding to Human Vimentin |
Uniprot ID: | P08670 |
Isotype: | IgG2a,κ |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm, Nucleus |
Predicted MW. / Observed MW. | 54 kDa / 54 kDa |
Product Usage Information
WB | Human | 1: 500-1: 1000 | Jurkat, A549, SW480 |
IHC/IF | Human, Rat | 1: 500-1: 1000 | kindey, esophageal carcinoma, colon cancer, colon, spleen, kindey |
Background
This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.
Images
| Western blot analysis of Vimentin-2 (GB121308) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human kindey using vimentin (GB121308) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human esophageal carcinoma using vimentin (GB121308) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human colon cancer using vimentin (GB121308) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat colon using vimentin (GB121308) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat spleen using vimentin (GB121308) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat kindey using vimentin (GB121308) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
