Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Vinculin rabbit polyclonal antibody |
Gene Name: | Vinculin |
Synonyms: | Metavinculin, Vcl, CMD1W, CMH15, MVCL, MV, VINC |
Immunogen: | Recombinant protein corresponding to Mouse Vinculin |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 117 kDa |
Observed MW. | 124 kDa |
Uniprot ID: | P18206, Q64727, P85972 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | heart, lung, uterus |
Background
Vinculin belongs to the vinculin/alpha-catenin family. It is an actin filament (F-actin)-binding protein which involved in cell-matrix adhesion and cell-cell adhesion. Vinculin regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It may also play important roles in cell morphology and locomotion.
Images
Western blot analysis of Vinculin (GB111328) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |