Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | ZIP Kinase rabbit polyclonal antibody |
Gene Name: | Death-associated protein kinase 3 |
Synonyms: | DAP kinase 3, DAP-like kinase, Dlk, MYPT1 kinase, ZIP kinase, Dapk3, Zipk, ZIP |
Immunogen: | Recombinant protein corresponding to Mouse ZIP Kinase |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Uniprot ID: | O54784 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 500-1: 2000 | brain, small intestine |
Background
DAPK3(Death-associated protein kinase 3) is also named as ZIPK(Zipper-interacting protein kinase),Dlk(DAP-like kinase). It is a member of the death-associated protein kinase family associated with apoptosis in nonmuscle cells where it phosphorylates myosin regulatory light chain (RLC) to promote membrane blebbing. DAPK3 mRNA and protein are abundant in heart tissue and isolated ventricular neonatal rat cardiac myocytes. It has 2 isoforms produced by alternative splicing,named as ZIPK-L and ZIPK-S. This antibody is specific to ZIPK-Phospho 311Ser.
Images
Immunohistochemistry of paraffin embedded mouse brain using DAPK3 (GB111907) at dilution of 1:1000 (300x lens) | |
Immunohistochemistry of paraffin embedded mouse small intestine using DAPK3 (GB111907) at dilution of 1:1000 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |