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Anti-alpha 2a Adrenergic Receptor Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | alpha 2a Adrenergic Receptor rabbit polyclonal antibody |
Gene Name: | Alpha-2A adrenergic receptor |
Synonyms: | Alpha-2A adrenoreceptor, Alpha-2A adrenoceptor, Alpha-2AAR, Adra2a, ZNF32, ALPHA2AAR, ADRAR, ADRA2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse alpha 2a Adrenergic Receptor |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 51 kDa |
Observed MW. | 51 kDa |
Uniprot ID: | Q01338, P22909 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 1000-1: 2000 | heart, kidney, liver |
Background
Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha 2A, alpha 2B, and alpha 2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha 2A and alpha 2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha 2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha 2C subtype modulated neurotransmission at lower levels of nerve activity.
Images
 | Western blot analysis of ADRA2 (GB112466) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
