Anti-alpha Actinin Rabbit pAb (100 μl)

Anti-alpha Actinin Rabbit pAb (100 μl)

Brand: ServiceBio
Cat. #: GB111556-100
Availability: In Stock
$259.00
-+
Reactivity: H,M,R & M,R    
Applications: WB & IHC/IF    
Host Species: Rabbit    
Clonality: Polyclonal    
Gene Name:

Alpha actinin

Synonyms:

Alpha-actinin cytoskeletal isoform, F-actin cross-linking protein, actinin, Non-muscle alpha-actinin-1, ACTN1, actinin 1 smooth muscle, Actn1a, BDPLT15, I79_004057

Immunogen:

KLH conjugated Synthetic peptide corresponding to Human ACTN1

Uniprot ID:

P12814

Isotype:

IgG

Purity:

Affinity purification

Subcellular location:

Cell membrane, Cytoplasm

Predicted MW. / Observed MW.

103 kDa / 103 kDa




Product Usage Information

WB

Human, Mouse, Rat

1: 500-1: 1000

spleen, skeletal muscle, heart

IHC/IF

Mouse, Rat

1: 500-1: 1000

kidney, liver, skeletal muscle




Background

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.




Images

1624872641998560783_0.jpg

Western blot analysis of tesk1 (GB11930) at dilution of 1: 1000
03 GB111556_alpha Actinin_M skin_5367_d900_21.5x_IHC.jpg Immunohistochemistry analysis of paraffin embedded mouse skin using Alpha-actinin (GB111556) at dilution of 1: 900
03 GB111556_alpha Actinin_M skeletal muscle_5367_d450_15.1x_IHC.jpg Immunohistochemistry analysis of paraffin embedded mouse skeletal muscle using Alpha-actinin (GB111556) at dilution of 1: 450

04 GB111556_alpha Actinin_M heart_5367_d500_45.0x_red_IF.jpg

Immunofluorescence analysis of paraffin embedded mouse heart using Alpha-actinin (GB111556) at dilution of 1: 500

05 GB111556_alpha Actinin_M skeletal muscle_5367_d500_24.4x_red_IF.jpg

Immunofluorescence analysis of paraffin embedded mouse skeletal muscle using Alpha-actinin (GB111556) at dilution of 1: 500

06 GB111556_alpha Actinin_M skin_5367_d500_17.5x_red_IF.jpg

Immunofluorescence analysis of paraffin embedded mouse skin using Alpha-actinin (GB111556) at dilution of 1: 500




Storage

Storage Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


Related Products


LifeSct © 2025

Publications

text_heading

Our Location

405 East Gude Dr., Suite 205, Rockville, MD 20850, USA

1-301-890-6420