Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | c-Kit rabbit polyclonal antibody |
Gene Name: | Mast/stem cell growth factor receptor Kit |
Synonyms: | KIT, C-Kit, CD117, PBT, SCFR, KIT proto-oncogene receptor tyrosine kinase |
Immunogen: | Recombinant protein corresponding to Mouse c-Kit |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 110 kDa |
Observed MW. | 145 kDa |
Uniprot ID: | P05532, P10721 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 400-1: 800 | lung, skin |
Background
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.
Images
Western blot analysis of C-Kit (GB11073-1) at dilution of 1: 400 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |