Reactivity: | H,M |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | cIAP2 rabbit polyclonal antibody |
Gene Name: | Baculoviral IAP repeat-containing protein 3 |
Synonyms: | Cellular inhibitor of apoptosis 2, Birc3, C-IAP2, Inhibitor of apoptosis protein 1, mIAP1, RING-type E3 ubiquitin transferase BIRC3, cIAP2 |
Immunogen: | Recombinant protein corresponding to Mouse cIAP2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 67 kDa |
Observed MW. | 67 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse | 1: 500-1: 1000 | Raji, HepG2, 293T, A431, THP-1, Jurkat, HL-60, K562, Raw264.7 |
Background
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals.
Images
Western blot analysis of IAP-2 (GB11892) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |