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Anti-hnRNP A1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | hnRNP A1 rabbit polyclonal antibody |
Gene Name: | Heterogeneous nuclear ribonucleoprotein A1 |
Synonyms: | hnRNP A1, HDP-1, Helix-destabilizing protein, Single-strand-binding protein, Topoisomerase-inhibitor suppressed, hnRNP core protein A1, Fli-2, Hnrpa1, Tis |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse hnRNP A1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Predicted MW. | 34 kDa |
Observed MW. | 34 kDa |
Uniprot ID: | P09651, P49312, P04256 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | spleen, uterus, ovary |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 2000 | brain, colon, rectum |
Background
HnRNP A1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre mRNAs in the nucleus and appear to influence pre mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. hnRNP A1 has two repeats of quasi RRM domains that bind to RNAs.
Images
| Western blot analysis of hnRNPA1 (GB111886) at dilution of 1: 500 |
| Immunohistochemistry of paraffin embedded mouse brain using hnRNPA1 (GB111886) at dilution of 1: 1000 (300x lens) |
| Immunohistochemistry of paraffin embedded rat brain using hnRNPA1 (GB111886) at dilution of 1: 1000 (300x lens) |
| Immunohistochemistry of paraffin embedded rat rectum using hnRNPA1 (GB111886) at dilution of 1: 1000 (300x lens) |
| Immunofluorescence of paraffin embedded human colon using hnRNPA1 (GB111886) at dilution of 1: 500 (300x lens) |
| Immunofluorescence of paraffin embedded rat brain using hnRNPA1 (GB111886) at dilution of 1: 500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
