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Anti-non-muscle Myosin IIB/MYH10 Mouse mAb (100 μl)
| Reactivity: | M |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Myosin-10 |
Synonyms: | Cellular myosin heavy chain, type B, Myosin heavy chain 10, Myosin heavy chain, Myh10, non-muscle IIb, NMMHC-B, NMMHC-IIB |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MYH10 |
Uniprot ID: | Q61879 |
Isotype: | IgG1,κ |
Purity: | Affinity purification |
Subcellular location: | Nuclear, Cytoplasm, Secreted |
Product Usage Information
IHC/IF | Mouse | 1: 500-1: 1000 | liver, liver cancer, glioma, kidney |
Background
MYH10 (non-muscle II-b, NM IIB) is a member of non-muscle myosin II which plays fundamental roles in the maintenance of cell morphology, cell adhesion, and migration, as well as cell division. MYH10 is mainly present in nerve cells, megakaryocytes, and other non-muscle cells. It has been reported to mediate centrosome reorientation during cell migration and contribute to ciliogenesis. Overexpression of MYH10 has been observed in breast cancer.
Images
| Immunohistochemistry analysis of paraffin-embedded mouse kidney using Myh10 (GB121186) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
