Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | p57 Kip2 rabbit polyclonal |
Gene Name: | Cyclin-dependent kinase inhibitor 1C |
Synonyms: | BWCR, BWS, CDKN1C, KIP2, p57, p57Kip2, WBS, Cyclin-dependent kinase inhibitor p57 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse p57 Kip2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 37 kDa |
Observed MW. | 55 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 1000-1: 2000 | pancreas |
Background
CDKN1C, also named as p57KIP2 and KIP2, belongs to the CDI family. CDKN1C is a potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. It is a negative regulator of cell proliferation. CDKN1C may play a role in maintenance of the non-proliferative state throughout life.
Images
Western blot analysis of p57 Kip2 (GB113714) at dilution of 1: 2000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |