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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Histone Deacetylase 3 (HDAC3) under CMV promoter. |
| Description: | Histone Deacetylase 3, pre-made adenovirus, ready to ship and ready to use format. |
| Gene: | Histone Deacetylase 3 |
| NCBI Acc. #: | BC000614 |
| Gene ID: | 8841 |
| GI Number: | 12653662 |
| Fusion Tag: | C-terminus V5 epitope tag |
| Promoter: | CMV |
| Titer: | 1x1011~1x1012 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. |
| Documents: | Please contact us to request the manual |
