siRNA Synthesis

siRNA Synthesis

Precision siRNA Synthesis for RNAi Applications

Small interfering RNA (siRNA) is a double-stranded RNA of 20 to 25 nucleotides, which can participate in RNA interference (RNAi) and play a role in silencing target genes. RNAi technology can specifically eliminate or turn off the expression of the target genes, and it has been widely used in gene function research and the treatment of infectious diseases and cancers. LifeSct provides research-grade custom siRNA synthesis services for gene silencing studies, oncology research, and therapeutic development. Our ISO9001-certified platform delivers 20-25nt double-stranded RNA with guaranteed gene knockdown efficiency.

siRNA Synthesis
 

Key Features

• Sequence-Specific Design: AI-optimized siRNA constructs with >90% silencing efficacy.
• Modification Flexibility: 2'-O-Me, phosphorothioate, fluorescent labeling options.
• Industrial-Scale Capacity: 1mg to 10g synthesis batches.
• HPLC-Validated Purity:  ≥98% purity with full MS/UV characterization.
 

Online Quote

Please click the button on the right side and login to your account to request a quote.
 

Service Options (Cat. #: S0013)

Custom siRNA Synthesis

Service Purification Starting Price (USD) Turnaround Time
Standard siRNA 1-2500 OD, HPLC $69 4-20 days
Modified siRNA HPLC Quote 4-20 days

siRNA Guaranteed Package

Service Purification Starting Price (USD) Turnaround Time
siRNA oligos of the target gene 3 pairs (3×2 OD) or
4 pairs (4×4 OD)
Quote Starting at 5 days
NC siRNA oligos 1 pair (1×1 OD) Quote Starting at 5 days
NC FAM siRNA oligos 1 pair (1×1 OD) Quote Starting at 5 days
Positive control siRNA oligos 1 pair (1×1 OD) Quote Starting at 5 days

Control siRNAs

Product Name Size Purification Status
NC siRNA 1 OD HPLC In stock
NC FAM siRNA 1 OD HPLC In stock
GAPDH Positive Control siRNA 1 OD HPLC In stock
P53 Positive Control siRNA 1 OD HPLC In stock
Beta-actin Positive Control siRNA 1 OD HPLC In stock

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