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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing human Lipocalin 2 (oncogene 24p3). |
| Description: | Pre-made adenovirus for over-expression of human Lipocalin 2 (oncogene 24p3), ready to ship and ready to use format. |
| Gene: | Lipocalin 2 (oncogene 24p3) |
| NCBI Acc. #: | NM_005564 |
| Gene ID: | 3934 |
| GI Number: | 5031852 |
| Fusion Tag: | No |
| Promoter: | CMV |
| Titer: | 1×1010~1×1011 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | The LCN2 gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice. |
| Storage: | -80°C |
| Documents: | Request a manual/MSDS |
