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Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3). |
Description: | Nuclear Receptor Subfamily 1, Group I, Member 3, pre-made adenovirus, ready to ship and ready to use format. |
Gene: | Nuclear Receptor Subfamily 1, Group I, Member 3 |
NCBI Acc. #: | BC069626.1 |
Gene ID: | 9970 |
GI Number: | 9970 |
Fusion Tag: | No |
Promoter: | CMV |
Titer: | 1x1010~1x1011 PFU/ml |
Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
Background: | NR1I3 gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. |
Documents: | Please contact us to request the manual |