Gene Synthesis

Gene Synthesis

By using our proprietary LiClone™ DNA synthesis and assembly platforms, the only thing you need to do is to tell us the DNA or amino acid sequences you are interested in. According to the DNA or amino acid sequences you provided, we will de novo synthesize the error-free DNA sequences and clone them into any vector as requested. In order to provide our customers with the highest quality service, Sanger sequencing will be conducted before each of these steps in order to verify the sequence accuracy. With our professional research team and effective systems in place, we promise you a one-stop location that will satisfy all of your gene synthesis needs.
 

Key Features

• Codon optimization software that provides free codon optimization services, enabling a significant increase in protein expression.
• LiClone™ Assembly technology ensures reliable assembly of long DNA fragments, single gene sequence up to 200 kb.
• Guarantee 100% sequence accuracy for all genes.
 

Online Quote

Please click the button on the right side and login to your account to request a quote. 
 

Service Options (Cat. #: S0012)

Custom Gene Synthesis

Gene Length Starting Price (USD)* Turnaround Time**
<600bp $120/gene  $109 10-12 business days
600bp-1500bp $0.20/bp  $0.18 10-12 business days
1501bp-3000bp $0.22/bp  $0.20 12-15 business days
>3000bp Quote Quote

* For complex genes, need to quote;
** Free for subcloning to usual vectors (download the list);
** $49 for subcloning to unusual vectors;
*** Turnaround time is dependent on length and complexity of the genes ordered. In a few cases, shipping time may exceed the estimated time.

Rush Gene Synthesis

Gene Length Starting Price (USD)* Turnaround Time**
<600bp $120/gene 5 business days
600bp-1500bp $0.29/bp 5-8 business days
1501bp-3000bp $0.35/bp 6-10 business days
>3000bp Quote Quote

* Not applicable to genes with complex sequences.


Delivery Forms

1. 1 tube of 2-5 μg lyophilized plasmid DNA
2. Original peak diagram of sequencing results,.ab1 format
3. COA file, including QC enzyme digestion verification figure
 

Publications

1. Rapid 40S scanning and its regulation by mRNA structure during eukaryotic translation initiation.  

Publication: Cell        Service: Gene Synthesis

2. HLA class I signal peptide polymorphism determines the level of CD94/NKG2–HLA-E-mediated regulation of effector cell responses.  
Publication: Nature Immunology        Service: Gene Synthesis

3. eEF2 diphthamide modification restrains spurious frameshifting to maintain translational fidelity.  

Publication: Nucleic Acids Research        Service: Gene Synthesis

4. The DNA Methyltransferase Inhibitor 5-Aza-4'-thio-2'-Deoxycytidine Induces C>G Transversions and Acute Lymphoid Leukemia Development. 

Publication: Cancer Research        Service: Gene Synthesis

Customer Testimonials

"Our lab started to use the high-quality services from LifeSct, including the gene synthesis and other molecular biology services since 2017. We are always happy with the great quality of the services, the reasonable price, the prompt shipment and the good communication from LifeSct. More impressively, your LiTaq™ PCR mix is robust and cost-effective. Thanks for continuing to produce great products and provide excellent services!"

------ NIH/NICHD, Dr. Chune Cao, Lab manager

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405 East Gude Dr., Suite 205, Rockville, MD 20850, USA

1-301-890-6420